SeYeon Chung
Associate Professor
CDIB Division
PhD: Seoul National University
Postdoc: Johns Hopkins University
Office: A208 Life Sciences Annex
Lab: A225/A229 Life Sciences Annex
Office: 225-578-1756
Lab Website:
Email: seyeonchung@lsu.edu
Twitter:
Area of Interest
My lab investigates the molecular and cellular mechanisms underlying tissue morphogenesis. The formation of three-dimensional tubular structures from flat epithelial sheets is a key process of organ formation in all animals, including mammalian lungs, kidney and digestive organs. Yet, we do not fully understand how such dramatic changes in tissue structures occur on a cellular level, and what molecular components regulate this fundamental process. My approach takes advantage of powerful Drosophila genetics, live imaging and computational analysis. Specifically, using Drosophila embryonic tubular epithelia as models, I seek to understand how the forces driving spatiotemporal changes in cell shape, arrangement and position are generated and transmitted during epithelial tube formation. These studies provide a basis for understanding general processes of organogenesis.
Selected Publications
Jeffrey Matthew, Vishakha Vishwakarma, Thao Phuong Le, Ryan A Agsunod and SeYeon Chung (2024) Coordination of cell cycle and morphogenesis during organ formation. .
Vishakha Vishwakarma, Thao Phuong Le and SeYeon Chung. (2022) Multifunctional role of GPCR signaling in epithelial tube formation. .
Sujin Nam, Thao Phuong Le, SeYeon Chung and Kwang-Wook Choi (2022) Tctp regulates the level and localization of Foxo for cell growth in Drosophila. .
SeYeon Chung, Thao Phuong Le, Vishakha Vishwakarma, Yim Ling Cheng and Deborah J Andrew (2021) Isoform-specific roles of the Drosophila filamin-type protein Jitterbug (Jbug) during development. .
Thao Phuong Le and SeYeon Chung (2021). Regulation of apical constriction via microtubule- and Rab11-dependent apical transport during tissue invagination. .
SeYeon Chung, Sangjoon Kim and Deborah J. Andrew (2017). Uncoupling apical constriction from tissue invagination. .
SeYeon Chung and Deborah J. Andrew (2014). Cadherin 99C regulates apical expansion and cell rearrangement during epithelial tube elongation. .
SeYeon Chung, Cy Chavez and Deborah J. Andrew (2011). Trachealess (Trh) regulates all tracheal genes during Drosophila embryogenesis. .
SeYeon Chung, Melissa S. Vining, Pamela L. Bradley, Chih-Chiang Chan, Keith A. Wharton, Jr. and Deborah J. Andrew. (2009). Serrano (Sano) functions with the planar cell polarity genes to control tracheal tube length. .
SeYeon Chung, Sangjoon Kim, Jeongsook Yoon, Paul N. Adler and Jeongbin Yim. (2007). The balance between the novel protein target of wingless and the Drosophila Rho-associated kinase pathway regulates planar cell polarity in the Drosophila wing. .
Review Papers
SeYeon Chung, Caitlin D. Hanlon and Deborah J. Andrew (2014). Building and Specializing epithelial tubular organs: the Drosophila salivary gland as a model system for revealing how epithelial organs are specified, form and specialize. .
SeYeon Chung and Deborah J. Andrew. (2008). The formation of epithelial tubes. .
Positions Available
We are recruiting PhD students. If interested, please email Dr. SeYeon Chung: seyeonchung@lsu.edu